The role of complex fractionated atrial electrograms in atrial fibrillation ablation moving to the beat of a different drum.
نویسندگان
چکیده
s physicians bid farewell to the last century, they also itnessed the rise of catheter-based ablation and the fall of ntiarrhythmic drug use for the treatment of cardiac arhythmias. At that time, only a select few investigators truly elieved that catheter-based ablation would work for treatent of atrial fibrillation (AF). The initial attempts at catheter ablation, patterned after he Cox surgical Maze procedure, were based on the natomical approach with empirically created multiple linar lesions in both atria. The catheter-based Maze ablation as short lived, however, because the procedure was diffiult, time-consuming, and associated with significant comlications. Fortunately, the breakthrough for AF ablation ame after Haïssaguerre et al. (1) described pulmonary veins PVs) as important sources of focal AF; they have since ecome the most important target for AF ablation.
منابع مشابه
Effects Of Fast Pathway Ablation On The Concealment Zone And Electrophysiological Behavior Of AV-Node During Atrial Fibrillation.
Objectives: Dual pathways have a determinant role in the occurrence of atrio nodal tachyarrhythmia (AVNRT). The aim of present study is to determine the role of slow pathway (SP) in the concealment zone and protective role of AV node during atrial fibrillation (AF). Material &Methods: In 7 isolated nodal rabbit preparation zone of concealment and concealed conduction is quantified by Specif...
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RATIONALE Electrogram-based catheter ablation, targeting complex fractionated atrial electrograms (CFAEs), is empirically known to be effective in halting persistent/permanent atrial fibrillation (AF). However, the mechanisms underlying CFAEs and electrogram-based ablation remain unclear. OBJECTIVE Because atrial fibrosis is associated with persistent/permanent AF, we hypothesized that electr...
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ورودعنوان ژورنال:
- Journal of the American College of Cardiology
دوره 53 9 شماره
صفحات -
تاریخ انتشار 2009